ArticleCUBOSOMES : NOVEL EMERGING DRUG DELIVERY SYSTEM
Manasi Nikam* , T. Vaishnavi Pai , Vasundhara J ,
Cubosomes are nanoparticles which are self assembled liquid crystalline particles of certain surfactants with proper ratio of water with microstructure that provides unique properties of practical interest. Bicontinuous cubic liquid crystalline phase is optically clear and very viscous material has the unique structure at nanometer scale. Conventional anticancer agents often fail because of their inability to distinguish cancer cells from normal cells resulting in severe toxic side effects. Cubosomes have the potential to improve the biodistribution of anticancer drugs by protecting them from degradation, delivering them directly to the tumour site. Cubosomes have potential in drug nano formulations for cancer therapy because of their advantages which include high drug loading capacity as they provide large internal surface area structures, simple preparation method, ability of encapsulation of hydrophobic, hydrophilic and amphiphilic drug, targeted and controlled release of many drugs.
Cubosomes, Nanoparticle, Cubic phase, Precursor, Liquid crystals, Melanoma