ArticleDetermination of Phytoconstituents & antioxidant Potential of extracts of fruit of Fragaria Vesca
Jeevan Menaria* , Dr. Jai Singh Vaghela, Ashok Choudhary
Fruits of Fragaria vesca it is belonging to vitaceae family, commonly known as strawberry available in every fruit seller. In these study try to findout antioxidant activity of these fruit. Prepare two different extract of fruit aqueous and ethanolic extract & find out Phytoconstituents and antioxidant activity of both extract. Fragaria vesca Phytoconstituents possess wide range of Phenolic, flavonoids compound possess. In vitro antioxidant was detected by DPPH assay, reducing power assay.The ethanolic, aqueous of fragaria vesca concentrates of & ascorbic acid exhibited antioxidant potential possessing IC50 48.14, 66.0 μg/ml & 14.40 μg/ml (Diphenylpicrylhydrazyl radical). The Reducing power assay possess 10.10, 11.51 μg/ml. Free radical scavenging difference due to solvent difference, it have better antioxidant activity which is helpful for controlling excess free radical in body Free radicals in body causes oxidative stress which is produced by reactive oxygen genus. It grow in cellular metabolism which may be in physiological cell at low to high concentration. It affects all over body systemic components.i.e. Lipids, Proteins, DNA etc. (Valko et al., 2006, Halliwel et al 2006, Marnett et al 1999). In our body possess wide number of free radicals present, it interfere with various electrons i.e. oxidation, reduction and produced oxidative stress, which is responsible for many pathological conditions, including cancer, neurological disorders (Siems et al 1995, Stadtman et al 2004, Wang et al 1996), atherosclerosis, hypertension, ischemia/perfusion (Jenner et al 2003,Lyras et Ial 1997), diabetes, acute respiratory distress syndrome, idiopathic pulmonary fibrosis, chronic obstructive pulmonary disease,and asthma (Sayre et 2001, Tosniwal et al 1997, Kukreja et al 1992) Free radicals has been possess electrically molecules, radicals responsible for oxidation, reduction, neutralization themselves. It possess unpaired electron, antioxidant are responsible for its activity or deactivity. Human body developed defensive mechanism to protect organ and cells against reactive oxygen species. Antioxidant i.e. ascorbic acid, Tocopherols, Carotenoids, Lipoic acid (Jacob et al 1995) Fragaria vescas leaf active constituents which are mainly present are cumene, α-pinene, thuja-2,4 - diene, β-pinene (Afzalzadeh el al., 2015), 3-p-menthene,6 hepten-2-ol,7 mentha-1(7), 8-dien, 8 hexenyl acetate,9 α-terpinene, p-cymene, limonene, β-ocimene (Z),β-ocimene, γ-terpinene, trans linalool oxide, terpinolene(Fontana et al., 2013), cis-linalool oxide, linalool, nonanal, menth-2-en-1-ol,trans-pinocarveol, cis verbenol,trans-verbenol, citronellal, menthone, pinocarvone, borneol, nonanol, mentha-1,5-dien-8-ol, menthol,terpinen-4-ol, cymen-8-ol, myrtenol(Yadav et al., 2009).
Fragaria vesca, Phytoconstituents, antioxidants.