Article

Spectrophotometric Determination of Esomeprazole in Tablet Dosage forms
Lingeswararao. P1* , Y. A. Chowdary, M. Ramakrishna, L. Rajesh Patro

Details

Author

Lingeswararao. P1*

ISSN

2319-5622

DOI

1

Published on

Nov 14, 2013

Abstract

A New, simple, sensitive spectrophotometric method in U.V region has been developed for the determination of Esomeprazole in bulk and in its dosage form. Esomeprazole shows maximum absorbance at 275 nm in Dimethyl formamide (DMF) solvent for first dilutio n and further dilution with 50:50 v/v of DMF:Water. Beers laws obeyed in the concentration range of 10-60mcg/ml.Results of analysis were validated statistically and by recovery studies

Keywords

Esomeprazole, Spectrophotometric Determination

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