Her research interests are to investigate molecular mechanisms underlying tumorigenesis and metastasis of ovarian and breast cancers, identify novel prognostic factors for early prognosis of ovarian and breast cancers, identify novel therapeutic targets for targeted therapy development for breast cancer, and develop targeted therapies for breast cancer. Specifically, my research focuses on triple-negative breast cancer (TNBC), the most aggressive type of advanced breast cancer for which effective targeted therapies are limited. TNBC is a subtype of breast cancer that is negative for estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2. TNBC accounts for 15-20% of all breast cancer cases and 30-40% of breast cancer deaths in the USA. I hope that my research leads to discovery of novel targets that can be used for development of targeted therapies, thereby reducing the mortality of patients with TNBC. (XXie2@mdanderson.org)

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